Bioactive Natural Products

Více o knize

Bioactive natural products are emerging as a valuable source for new therapeutics to prevent and treat diseases, as well as for crop protection. This volume builds on the first edition, compiling research from new contributors and highlighting the successful detection, isolation, and structural determination of specific compounds. It covers a wide variety of techniques applicable to both terrestrial and aquatic sources, guiding readers on how to select source material to enhance the discovery of novel bioactive products. New features in this edition include advancements in NMR spectroscopy, mass spectrometry, bioactive chemical detection, extraction methods, dereplication, and novel bioassay development. It presents new case studies and illustrations that showcase the practical application of these techniques. The text begins with an overview of natural product chemistry, followed by chapters on source material selection, quantitative NMR, high-speed counter-current chromatography, and stereochemistry determination. Additionally, it explores new technologies such as LC-NMR, biosensors, and biofingerprinting, alongside discussions on anticancer and antimalarial activities, seed germination stimulation, and mammalian toxicity. With contributions from active researchers, this work serves as a significant resource for the detection, isolation, and structural determination of bioactive natural products.