Problems and Solutions in Biological Sequence Analysis

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This book offers a comprehensive collection of bioinformatics problems with detailed solutions, addressing a significant gap in the field. It includes all problems from Biological Sequence Analysis (BSA) by Durbin et al., a widely used text in bioinformatics courses at top universities. While many BSA exercises have been used for homework and exams, the lack of detailed solutions has been a challenge for instructors. This resource not only provides fully worked solutions but also expands the problem set, enhancing understanding of BSA's chapters and fostering essential problem-solving skills for research in bioinformatics. The material has been rigorously tested by the authors at Georgia Tech, home to the first M.Sc. program in Bioinformatics. Mark Borodovsky, a Regents' Professor of Biology and Biomedical Engineering and Director of the Center for Bioinformatics and Computational Biology at Georgia Institute of Technology, has been instrumental in establishing bioinformatics education since 1994. Svetlana Ekisheva, a Research Scientist at the same institution, brings expertise in bioinformatics, applied statistics, and teaching probability theory and statistics in both Russia and the USA. This book is an invaluable resource for students and educators in the field.