Yehuda Shoenfeld Knihy

Imunologie je mladá medicínská disciplína, která se prolíná všemi lékařskými obory. Téma autoimunitních chorob je aktuální a kniha osloví praktické lékaře i specialisty, zejména starší generace, kteří se o těchto onemocněních během studií neučili. Kniha slouží jako poučný a přitom odlehčený materiál pro studenty medicíny a přírodních věd. Složitá problematika autoimunity je podána jasně a srozumitelně, i když zjednodušeně. Základní funkce imunitního systému a okolnosti vedoucí k sebepoškozujícímu zánětu, který může vyústit v chronická onemocnění, jsou stručně popsány. Upozorňuje na nevhodnost posilování "oslabené imunity", která ve skutečnosti selhává nepřiměřenými reakcemi. Kniha zahrnuje přehled různých autoimunitních chorob, jako jsou roztroušená skleróza, cukrovka I. typu a revmatoidní artritida, které mají podobnou patogenezi a léčbu. Samostatné kapitoly se věnují jak patogenezi, tak možnostem léčby těchto onemocnění. Doplňují ji souhrnné tabulky, barevná příloha s typickými klinickými příznaky autoimunitních chorob, rejstřík a odkazy na další specializovanou literaturu.

According to the Autoimmune Diseases Coordinating Committee (ADCC), between 14.7 and 23.5 million people in the USA – up to eight percent of the population are affected by autoimmune disease. Autoimmune diseases are a family of more than 100 chronic, and often disabling, illnesses that develop when underlying defects in the immune system lead the body to attack its own organs, tissues, and cells. In Handbook of Autoimmune Disease, the editors have gathered in a comprehensive handbook a critical review, by renowned experts, of more than 100 autoimmune diseases, divided into two main groups, namely systemic and organ-specific autoimmune diseases. A contemporary overview of these conditions with special emphasis on diagnosis is presented. Each chapter contains the essential information required by attending physicians as well as bench scientists to understand the definition of a specific autoimmune disease, the diagnostic criteria, and the treatment.

This is the third volume of a series of four on autoimmunity, and findings related to particular organs, organ systems, and diseases are presented. The focus in Part C is on autoimmunity and vessel pathology, the neurologic system, cancer, the GI tract, diabetes, the lung, and the heart.

The incidence of autoimmune diseases is increasing worldwide, and the search for better management of these diseases and even for a cure is being pursued by scientists from many disciplines. Tools from the areas of genetics, neuroscience, cell biology, virology, and infectious disease are being applied to the problem and are yielding useful results. This is the fourth and final volume of a series on autoimmunity, and findings related to particular clinical manifestations are presented, particularly systemic lupus erythematosus, scleroderma, rheumatoid arthritis, Sjogren's syndrome, antiphospholipid antibodies, and infections and autoantibodies. Part A presents new principles in autoimmunity and new diagnostic tools; Part B focuses on genetics and advances in treatment; and Part C begins the focus on the clinical venue. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit . ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order ( ). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit for more information about becoming a member