Thomas M. Devlin Knihy

This newly revised and updated fifth edition of Devlin's Textbook of Biochemistry with Clinical Correlations presents the biochemistry of mammalian cells, relates events at the cellular level to physiological processes in the whole animal, and cites examples of human diseases derived from aberrant biochemical processes. This edition significantly expands the clinical correlation that highlight the significance of biochemistry to specific clinical problems. Full-color illustrations provide clear explanations for the concepts discussed, and end-of-chapter questions and answers act as challenging study material. Reorganized into five practical sections, Textbook of Biochemistry with Clinical Correlations covers these topics and much more: Structure of macromolecules-DNA, RNA, and protein structure Information transmission-replication, transcription, protein synthesis, and control of gene expression Functions of proteins-protein families, enzymes, membrane structure, and transport mechanisms Metabolic pathways and their control-carbohydrate, lipid, amino acid, and nucleotide metabolism Physiological processes-hormone and signal transduction, biochemistry of nervous tissue, muscle vision, coagulation and digestion, and principles of nutrition

Entirely revised and updated, this edition provides comprehensive, in-depth coverage of the subject. Each chapter includes an overview, a thorough treatment of the topic, followed by a bibliography and questions and answers. Unique to this book is the inclusion of clinical correlations which describe clinical examples of the consequences of malfunctioning biochemical pathways. The book introduces the chemistry and structure of cells and proceeds with discussion on proteins, enzymes, membrane structure and function, bioenergetics, metabolism of carbohydrates, lipids, amino acids and nucleic acids. It also covers all aspects of molecular biology.