Gerhard Rogler Knihy

As the number of children with IBD is increasing, the interaction between pediatric and adult gastroenterology is gaining importance to facilitate the transition from childhood into adulthood. Moreover, it is important to take into account not only the potential differences in phenotypes and clinical evolution of IBD during the life cycle, but also the changes in environmental factors and the possible differences in patient response resulting from the latter. The articles contained in this publication are based on the presentations made during the Falk Symposium on ‘IBD in different age groups’ in Madrid in 2009. On this occasion, specialists in adult and pediatric gastroenterology have gathered for the first time to exchange information with regard to differences in pathogenesis, clinical manifestations, evolution and therapeutic approaches to IBD. Presenting an integrated view of the disorder, the papers of this publication will be a great help for every doctor treating IBD patients in any age group.

In daily medical practice, physicians often use scores, classifications and schematic diagnostic paths to make clear and comprehensive decisions. Treatment algorithms have also proven to be effective. However, it has become increasingly difficult or even impossible to have all scores, schemata and algorithms at hand, and a search on the internet can be very time consuming. Gastrix solves this problem: unlike classic gastroenterology and hepatology textbooks, it summarizes all necessary information in the form of a pocket-sized book. Gastroenterologists will thus have all relevant information easily available at all times.

This special topic issue of 'Digestive Diseases' contains contributions discussing the subject in-depth. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in gastroenterology. Special topic issues are included in the subscription.

The introduction of anti-tumour necrosis factor (TNF) antibodies into the treatment of patients with IBD about fifteen years ago has dramatically improved the quality of life for patients with severe Crohn's disease and ulcerative colitis. But despite the fact this therapeutic approach has been around for quite some time, there has been no comprehensive overview to date. The book at hand aims to amend this shortcoming, presenting for the first time a thorough overview on TNF action, mechanisms of anti-TNF therapy, treatment strategies, side effects, monitoring, biosimilars and related issues. Including state-of-the-art information and research results, this publication will be a valuable source of information and guide clinicians to the optimal treatment decision, improving the quality of life of patients with inflammatory bowel disease. Moreover, rheumatologists or even dermatologists might also find this book of interest.

Supplement Digestive Diseases 2012, Vol. 30, Suppl. 3 This issue is a dedicated supplement published in addition to the regular issues of 'Digestive Diseases' focussing on one specific topic. 'Digestive Diseases' is a well-respected, international peer-reviewed journal in Gastroenterology. Supplement issues are included in the subscription.

In den letzten Jahren hat das Wissen über chronisch entzündliche Darmerkrankungen deutlich zugenommen. Im Bereich der Pathophysiologie wurden wichtige Erkenntnisse gewonnen und die Zahl der Risikogene für diese Erkrankungen ist sprunghaft gestiegen. Auch im Bereich der Therapie zeichnen sich neue Optionen ab, die damit komplexer werden wird. Dieses Buch möchte in der vorliegenden 3. Auflage das erweiterte Wissen vermitteln. Es berücksichtigt u. a. die Ergebnisse der Schweizer Kohorten Studie (SIBDC) und ist eine wertvolle Unterstützung für alle, die Patienten mit chronisch entzündlichen Darmerkrankungen behandeln.