Tato série shromažďuje příběhy osamělých hrdinů z Marvelova univerza, kteří se spojí tváří v tvář nové, smrtící hrozbě. Když starý nepřítel povstane a snaží se sjednotit podsvětí, ikonické postavy jako Daredevil, Luke Cage, Jessica Jones a Iron Fist musí odložit své rozdíly. Společně se stávají silou, kterou nelze ignorovat, a chrání město před temnými silami, které ho ohrožují.
Daredevil! Luke Cage! Jessica Jones! Iron Fist! Individually, these four heroes have been on the front lines of the battle to keep the streets of the city safe and secure. But now, with a deadly enemy from the dim past making a major move to unite the underworld, they will need to become more... they will need to become...DEFENDERS!
The Defenders - Iron Fist, Jessica Jones, Luke Cage and Daredevil, protectors of the people - are in a desperate struggle to keep New York City safe in the wake of the power vacuum caused by the Kingpin's absence and the all-out street war that results! So what could make things even worse for our team of harried heroes? Would you believe - Deadpool? The Kingpin's kingdom is up for grabs, and the streets of Marvel will burn as every major underworld figure makes a play to be the next kingpin of crime! Unfortunately for them, this is exactly why the Defenders have gathered - to make our streets a safer place! But bad press is about to have a disastrous impact on Luke's and Jessica's lives. And how exactly does Diamondback know so much about the Defenders? COLLECTING: DEFENDERS 6-11