Raz Jelinek Knihy

Addressing one of the biggest riddles in current molecular cell biology, this ground-breaking monograph builds the case for the crucial involvement of lipids and membranes in the formation of amyloid deposits. Tying together recent knowledge from in vitro and in vivo studes, and built on a sound biophysical and biochemical foundation, this overview brings the reader up to date with current models of the interplay between membranes and amyloid formation. Required reading for any researcher interested in amyloid formation and amyloid toxicity, and possible avenues for the prevention or treatment of neurodegenerative disorders. From the contents: * Interactions of Alpha-Synuclein with Lipids * Interaction of hIAPP and its Precursors with Membranes * Amyloid Polymorphisms: Structural Basis and Significance in Biology and Molecular Medicine * The Role of Lipid Rafts in Alzheimer's Disease * Alzheimer's Disease as a Membrane-Associated Enzymopathy of Beta-Amyloid Precursor Protein (APP) Secretases * Impaired Regulation of Glutamate Receptor Channels and Signaling Molecules by Beta-Amyloid in Alzheimer's Disease * Membrane Changes in BSE and Scrapie * Experimental Approaches and Technical Challenges for Studying Amyloid-Membrane Interactions and more

Exploring the convergence of biological and non-biological realms, this book delves into the advancements in understanding biological phenomena and the manipulation of molecular systems. It systematically covers artificial and synthetic assemblies that replicate living systems, highlighting applications in biomaterials, drug discovery, microelectronics, and computer sciences. The text offers insights into how these innovations are reshaping our perception of life and technology.

Nanoparticles presents the variety of nanoparticle families, structures, and functions. The book discusses nanoparticles made of semiconductors, metals, metal-oxides, organics, biological and hybrid constituents. Through a wealth of examples and cas

Unveränderter Nachdruck der Originalausgabe von 1850.

This book introduces the various aspects of the emerging field of carbon dots. Their structural and physico-chemical properties as well as their current and future potential applications are covered. A special chapter on graphene quantum dots is provided. The reader will also find different synthesis routes for carbon quantum dots.

Describes the properties of cellular membranes and their relationship with fundamental biological processes. This book provides insight on the chemistry, structures, model systems, and techniques employed for studying membrane properties and processes. A major focus is on the prominence of membranes in diverse physiological processes and disease, as well as applications of membranes and biomimetic membrane systems in varied disciplines. The book aims to illuminate the significance and beauty of membrane science, and serve both as an entry point for scholars wishing to embark on membrane research, as well as scientists already working in the field.

Biological systems have always inspired mankind in the creation of new systems and technologies. In recent years the interface between the biological and non-biological worlds appears increasingly blurred due to significant advances both in our understanding of biological phenomena, as well as the development of sophisticated means to manipulate molecular systems for varied applications. Biomimetics as a distinct discipline shows how biology and biological processes are manifested in diverse aspects of chemistry, physics and engineering. This book aims to methodically describe artificial and synthetic assemblies mimicking biological and living systems - from biomaterials to drug discovery to microelectronics and computer sciences.

With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine. The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.