Knihobot

Herbert Pfister

    Prophylaxis and early detection of HPV-related neoplasia
    Inertia and Gravitation
    • Inertia and Gravitation

      The Fundamental Nature and Structure of Space-Time

      • 192 stránek
      • 7 hodin čtení

      This book delves into inertia and gravitation, aiming to illuminate the laws of gravitational interaction and the nature of spacetime. Chapter 1 offers a comprehensive analysis of the law of inertia, presenting the mathematical and geometrical framework of Newtonian spacetime from a four-dimensional perspective. It critically examines historical challenges related to free particles and straight lines, while also connecting to projective geometry. Chapter 2 explores the relativistic extensions of gravitation, building on the works of Weyl, Ehlers, Pirani, and Schild, and emphasizes Mach’s critique of Newton’s notions of ‘absolute space’ and ‘absolute time’ as a key influence on Einstein’s general relativity. The chapter highlights how Einstein’s equivalence principle reshaped the understanding of inertia. Chapter 3 focuses on the unique mathematical structure of Einstein’s field equations, showcasing some of their notable physical predictions. In Chapter 4, different types of dragging phenomena are analyzed to assess the realization of the equivalence principle in general relativity. This discussion is closely tied to the concept of gravitomagnetism, a 'new force' theorized by Einstein and Thirring, which has gained attention following recent experimental confirmations.

      Inertia and Gravitation
    • Human papillomaviruses (HPV) are a heterogeneous and still growing virus family. Topical research results on the replication cycle and carcinogenic mechanisms allow a better understanding of current prevention strategies. Written by leading experts, this volume of Monographs in Virology provides up-to-date information on the prevention of papillomavirus-induced cancers by prophylactic antiviral vaccines and early detection of precancerous lesions. A major section covers the tremendous clinical burden due to HPV infections: genital warts and laryngeal papillomas, the most notorious cervical cancer, but also further anogenital and tonsillar cancer, the incidence of which increased steeply during the last decades. Additionally, a section on prevention addresses the subject cytology - new concepts of biomarker development, detection of HPV DNA and RNA as well as their use in primary screening for early detection of precancerous lesions. Finally the book closes with a topical discussion of the most intriguing primary prevention of HPV infection by vaccination. As new perspectives for the prevention of HPV-related neoplasia raised great public interest, this book will be of value to clinicians and practitioners in gynecology, dermatology, urology and ENT, to pathologists, laboratory physicians, medical students, and public health authorities.

      Prophylaxis and early detection of HPV-related neoplasia