Theory, Reactivity and Mechanisms in Modern Synthesis
1678 stránek
59 hodin čtení
Focusing on the essentials of reactivity, reaction mechanisms, and thermodynamics, this textbook serves as a crucial resource for both students and researchers in physical organic chemistry. It combines theoretical knowledge with practical exercises, ensuring a thorough understanding of fundamental concepts necessary for successful organic reactions.
This textbook provides essential background, tools, and models for understanding organic synthesis and planning chemical reactions efficiently. A solid grasp of physical chemistry is crucial for successful reactions in organic chemistry, requiring chemists to be skilled in various areas. The text, authored by two recognized experts, addresses a gap in the literature on physical organic chemistry. It begins with rigorous yet accessible chapters on chemical equilibria, thermodynamics, reaction rates, mechanisms, and molecular orbital theory, establishing a strong foundation. Subsequent chapters showcase diverse reactions involving organic, organometallic, and biochemical reactants and catalysts. With over 800 questions and exercises, the text reinforces comprehension and emphasizes key learning points. A companion workbook provides complete references and answers to all questions. This resource is invaluable for students and working chemists, presenting models to assess reaction feasibility, duration, and properties. It covers reactions with significant practical applications, including C-C coupling, pericyclic, and catalytic reactions, enabling efficient planning of chemical reactions. The textbook features clear illustrations, figures, and tables, and includes a Foreword by Nobel Prize Laureate Robert H. Grubbs, making it an ideal reference for chemistry students, instructors, and professionals in organic and physical chemistr