Significant progress has been made in developing efficient oxyfunctionalization bioprocesses using oxygenases in heterotrophic whole-cell systems. However, challenges such as limited O2 supply and reliance on carbohydrate-based electron sources hinder their industrial application regarding production rates and costs. Utilizing phototrophic organisms as whole-cell biocatalysts for oxygenase-based biotransformations presents a promising alternative for eco-efficient production of oxyfunctionalized chemicals. While various cyanobacterial and microalgal bioprocesses for CO2-derived fermentations have been established, processes that generate activated reduction equivalents and O2 from photosynthetic water oxidation remain scarce. Current research primarily focuses on engineered catalysts aimed at hydrogen production, but a comprehensive bioprocess design for phototrophic organisms in redox biotransformations is still absent. This thesis seeks to integrate biotechnological methods and strategies to develop eco-efficient, photosynthesis-driven oxyfunctionalization processes. The main research question explores the conceptual evaluation of photosynthetic electron and O2 supply alongside the technical feasibility of using cyanobacteria as phototrophic hosts in hydrocarbon oxyfunctionalization bioprocesses. By employing an integrated bioprocess design framework, various engineering tools are utilized to establish innovative, photosynth
