Functional heterogeneity of liver tissue

Tissue heterogeneity is a subject of long-standing interest in liver pathophysiology. Recent advances in the cell and molecular biology of hepatocytes and sinusoidal cells have yielded new insights into how liver cells differentiate and establish their functional compartmentation at the hepatic lobule level. This book contains a collection of reviews on the current cellular and molecular concepts supporting the functional units of liver tissue and their impact in disease. To understand the pathogenesis of liver diseases it is necessary to know about the different liver cell properties and their functional interdependencies. This book describes interrelated hepatic cell functions and dysfunctions, providing a more comprehensive view of liver tissue functioning homeostasis.