Fluoroquinolone Antibiotics

InhaltsverzeichnisThe history of quinolones.Structure-activity relationships of quinolones.Epidemiology and mechanisms of resistance.Improved safety profile of newer fluoroquinolones.Pharmacokinetics and pharmacodynamics (PK/PD) of fluoro-quinolones: tools for combating bacteria and preventing resistance.Fluoroquinolones in urinary tract infection.The quinolones and sexually transmitted infections.Gastrointestinal and intraabdominal infections.The quinolones in otitis media and upper respiratory infections.Quinolones in pneumonia.Fluoroquinolones for the treatment of respiratory tractinfections other than pneumonia.Quinolones for the treatment of skin, soft tissue, bone andprosthetic joint infections.The role of fluoroquinolones in the therapy and prophylaxisof neutropenic patients with cancer.Less usual indications: Mycobacterial, Brucella, Yersinia, Francisella and other infections.The quinolones: future prospects.