Absolute laser spectrometric amount fraction

The aim of this work was to: perform absolute amount fraction measurements of breath gas species using TDLAS, QCLAS and CRDS, reliably quantify breath gas species, address metrological data quality objectives, i. e. uncertainty and traceability issues, as well as define and reduce the uncertainty of amount fraction results from the typical 10 % to levels suitable to fit breath analysis purposes, 5 % and below. Thus, aiming at traceable amount fraction results, measurements have been performed using TDLAS, QCLAS and CRDS based on the absolute method TILSAM. GUM compliant uncertainty budgets for spectrometric amount fraction results were developed.