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Focusing on confirmatory adaptive designs, this book offers a comprehensive review of their principles and techniques, emphasizing their evolution from group sequential designs. It details the process of conducting interim analyses to potentially halt trials while managing Type I error rates. Additionally, the text covers the flexibility of adaptive designs, allowing for data-driven modifications such as reassessing sample sizes, selecting treatment arms, or identifying specific sub-populations during the study.
Nákup knihy
Group Sequential and Confirmatory Adaptive Designs in Clinical Trials, Gernot Wassmer, Werner Brannath
- Jazyk
- Rok vydání
- 2016
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- (pevná)
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Doručení
Platební metody
Navrhnout úpravu
- Titul
- Group Sequential and Confirmatory Adaptive Designs in Clinical Trials
- Jazyk
- anglicky
- Autoři
- Gernot Wassmer, Werner Brannath
- Vydavatel
- Springer International Publishing
- Rok vydání
- 2016
- Vazba
- pevná
- Počet stran
- 320
- ISBN13
- 9783319325606
- Kategorie
- Zdraví / Medicína / Lékařství, Matematika
- Anotace
- Focusing on confirmatory adaptive designs, this book offers a comprehensive review of their principles and techniques, emphasizing their evolution from group sequential designs. It details the process of conducting interim analyses to potentially halt trials while managing Type I error rates. Additionally, the text covers the flexibility of adaptive designs, allowing for data-driven modifications such as reassessing sample sizes, selecting treatment arms, or identifying specific sub-populations during the study.