Janeway's Immunobiology

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This textbook introduces the immune system comprehensively for undergraduates, while also serving graduate students and medical students. The thoroughly revised Eighth Edition is available in print and e-book formats, maintaining a standard of clarity, organization, and scientific accuracy. It emphasizes the host's interaction with potentially harmful microorganisms, supported by a coherent full-color art program that illustrates key processes and mechanisms. The 16 chapters are organized to facilitate a complete one-semester immunology course, covering topics from innate to adaptive immunity and applied clinical immunology. Discussion questions at the end of Chapters 2 to 16 aid in review and class discussions, with summaries concluding each section. Notably, the Eighth Edition expands on innate immunity across two chapters, detailing antimicrobial peptides and cellular innate receptors. The text integrates evolution, enhancing students' understanding of immune strategies across organisms. Key chapters have been updated, including B-cell immune responses and mucosal immunity, reflecting current knowledge on microbiota and tolerance. The chapter on host defense failures has been reorganized to clarify primary immunodeficiencies, while the chapter on manipulating the immune response emphasizes clinical issues and updates on immunotherapeutics and vaccines. New figures and references throughout enhance the learning experience.