DNA Mismatch Repair and Checkpoint System during Meiosis

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The research focuses on T. thermophila as a model organism for studying DNA mismatch repair (MMR) and meiotic checkpoint systems. Its large single-cell structure facilitates chromosome analysis, while its inducible conjugation allows exploration of protein functions during meiosis. The book delves into the relationship between meiotic checkpoints and MMR, addressing the unresolved mechanisms of meiotic checkpoints and enhancing our understanding of genomic integrity in eukaryotes.