Hormones and Resistance

The exploration of hormonal influence on drug resistance is central to this work, emphasizing the need for detailed pharmacokinetic analysis. It discusses the importance of identifying which hormones confer protection against specific drugs before investigating their mechanisms. Observations, such as the protective role of ethylestrenol against indomethacin-induced ulcers, highlight the complexity of hormonal interactions. The text suggests that indirect indicators often guide scientific discovery, paralleling methods used in both chemistry and medicine to identify substances or pathogens.