Linda L. Gallo Pořadí knih

Atherogenesis: Lipid Accumulation and Plaque Disruption: Processes Triggering Clinical Instability in Coronary Disease-An Overview; B.G. Brown. Expression of 92 kDa Gelatinase in Human Atherosclerotic Lesions Following Recent Plaque Rupture; D.L. Brown. Atherogenic Lipoproteins: Current Concepts of the Plasma Lipoproteins and Their Role in Atherosclerosis-An Overview; H.B. Brewer, Jr. Homeostasis of Lipid Oxidation in the Artery Wall; A.M. Fogelman, et al. Antiatherogenesis/Cholesterol Removal Mechanisms: The Role of HDL Receptors in Removal of Cellular Cholesterol; J.F. Oram, et al. Signal Transduction in Vascular Proliferation: Identification of FGF1-Inducible Genes by Differential Display; J.A. Winkles, et al. Adhesion Pathobiology: Molecular Basis and Pathological Consequences of Neutrophil Adherence to Endothelium; J.M. Harlan, et al. Thrombosis/Fibrinolysis: Regulation of Vascular Fibrinolysis by Type 1 Plasminogen Activator Inhibitor (PAI1): D. Seiffert, et al. Modified Gene Expression/Clues to Cause, Prevention, and Treatment of Atherosclerosis: Genetic Factors Contributing to Atherosclerosis: From Humans to Mice and Back Again; C.H. Warden, A.J. Lusis. Atherosclerosis Prevention and Public Policy: Cholesterol and Mortality: What Can Metaanalysis Tell Us? D.J. Gordon. 35 additional articles. Index.

The Sixth Annual International Spring Symposium on Health Sciences, held in Washington, D.C. in May 1986, gathered over 650 scientists from 19 countries to review research on cardiovascular disease. This volume features 59 chapters authored by internationally recognized experts, providing current insights into molecular and cellular processes in atherogenesis and strategies for preventing and treating atherosclerosis. The text is organized into six major sections. The first two focus on lipoprotein metabolism. Part I highlights the impact of structural heterogeneity within lipoprotein classes on metabolism and discusses the components that regulate this process, including apolipoprotein identities, processing, functions, and the roles of lipid transfer proteins in plasma lipoprotein remodeling. It also covers hepatic lipase synthesis and secretion. In Part II, Nobel Laureates Michael S. Brown and Joseph L. Goldstein examine mutations in the LDL receptor, elucidating its functional domains and how this knowledge aids in understanding its regulation. The section further explores the role of receptors in cholesterol uptake by tissues, emphasizing receptor-ligand interactions, and discusses additional pathways for cholesterol delivery and egress from cells.