Cell adhesion molecules and matrix proteins

Both scientific research and commercial interest in investigating the role of cell adhesion molecules in complex cell-cell and cell-matrix interactions are growing at a rapid pace. The recent identification and manipulation of an expanding number of cell adhesion molecules (CAMs) provide an excellent opportunity for therapeutic and diagnostic interventions in a wide variety of disease processes including acute and chronic inflammatory diseases, vascular remodeling, autoimmune and thrombotic disorders, neurodegenerative complications, bacterial adhesion, angiogenesis and restenosis.