Ionotropic glutamate receptors in the CNS

InhaltsverzeichnisSection I: Molecula r Structure of Glutamate Receptors.1 Structure of Ionotropic Glutamate Receptors.2 Phosphorylation of Glutamate Receptors.3 The Synaptic Protein Network Associated with Ionotropic Glutamate Receptors.4 Cellular and Subcellular Distribution of Glutamate Receptors.Section II: Functional Properties of Glutamate Receptors.5 Activation of Single AMPA- and NMDA-Type Glutamate-Receptor Channels.6 The Ion-Conducting Pore of Glutamate Receptor Channels.7 Block of AMPA and Kainate Receptors by Polyamines and Arthropod Toxins.8 Kainate Receptors.9 Molecular Determinants Controlling Functional Properties of AMPARs and NMDARs in the Mammalian CNS.Section III: Glutamatergic Synaptic Transmission.10 Morphological Characteristics of Glutamatergic Synapses in the Hippocampus.11 Glutamate-Mediated Synaptic Excitation of Cortical Interneurons.12 Physiology of Glutamatergic Transmission at Calyceal and Endbulb Synapses of the Central Auditory Pathway.13 Glutamate Transporters and Their Contributions to Excitatory Synaptic Transmission.Section IV: Involvement of Glutamate Receptors and Transporters in Neurological Diseases.14 Glutamate-Mediated Excitotoxicity.15 Glutamate Transporter Dysfunction and Neuronal Death.16 NMDA Recepor Antagonists and Their Potential as Neuroprotective Agents.