Cologne Atherosclerosis Conference No. 2: Lipids

InhaltsverzeichnisLipoprotein Synthesis and Receptor Interactions.- Apolipoprotein genes, DNA polymorphisms and hyperlipidaemia.- The use of recombinant DNA technology to study polygenic hyperlipidaemia.- Lipoprotein synthesis (Abstract only).- The LDL receptor in lipoprotein turnover (Abstract only).- Receptor interactions controlling lipoprotein metabolism (Abstract only).- A saturable binding site for high density lipoprotein3 on human liver membranes.- Lipoprotein Metabolism.- Lipoprotein lipase — the molecule and its interactions.- Organ specific metabolism of low density lipoprotein and high density lipoprotein.- Metabolism of rat serum high-density lipoprotein apolipoprotein A-IV.- Importance of particle size and lipid composition in the transfer of plasma apolipoproteins to microemulsions.- The role of lysophosphatidylcholine in the regulation of the catabolism of triglyceriderich lipoproteins.- Hypercholesterolemic and diabetic serum decrease LDL-degradation by cathepsin D from human arterial smooth muscle cells and fibroblasts.- Metabolic channelling of apolipoprotein B in very low density lipoprotein.- Turnover of APOB in low density lipoprotein sub-fractions.- Lipoproteins and Macrophages.- Degradation of normal and abnormal plasma lipoproteins by cultured macrophages.- The role of macrophages in atherosclerosis (Abstract only).- The role of the monocyte/macrophage system in lipoprotein metabolism.- Solubilization and purification of an acetyl-LDL binding membrane protein from human leukocytes.- The effect of LDL and modified LDL on macrophage secretion products.- Macrophages, oxidised lipids and atherosclerosis.- Clinical Aspects.- Regulation of low density lipoprotein uptake and degradation in different animal species.- Regulation of LDL receptors in vivo.- Familialhypercholesterolemia proven by tissue culture and atherosclerosis in relation to other risk factors.- Familial hypertriglyceridemia and the regulation of lipid synthesis by insulin and triiodothyronine in human cell cultures.- Mutations of apolipoprotein AI can affect cofactor function for cholesteryl ester formation by lecithin: cholesterol acyltransferase.- Oral administration of polyunsaturated phosphatidylcholine reduces lipid and cholesterol contents in platelets of healthy volunteers.- Influence of age, body-weight, smoking habits and alcohol consumption on the lipoprotein profile: preliminary results from a study performed on 6543 male industrial workers aged 40–59 years.