Proteases, Protease Inhibitors and Protease-Derived Peptides

InhaltsverzeichnisOverview.Proteases — Structures, Mechanisms and Inhibitors.Biochemical Mechanisms for Disrupting the Proteinase-Proteinase Inhibitor Balance in Tissues.Oxidants, Metalloproteases and Serine Proteases in Inflammation.Elastase and Oxygen Radicals: Synergistic Interactions.Neutrophil Elastase Inhibitors: Clinical Potential.Proteolysis-Induced Pathomechanisms in Acute Inflammation and Related Therapeutic Approaches.Synthesis and Characterization of Human Neutrophil Elastase Inhibitors Derived from Aromatic Esters of Phenylalkanoic Acids.In Vivo Evaluation of MDL 201,404YA, A Novel Inhibitor of Human Neutrophil Elastase.Alpha1-Antitrypsin Augmentation Therapy.Secretory Leukocyte Protease Inhibitor in Cystic Fibrosis.Oxidation Resistant Muteins of Antileukoproteinase as Potential Therapeutic Agents.Proteases and Protease-Derived Peptides in Inflammation.Factor XII Activation and Inhibition in Inflammation.The Kinin System in Inflammation.Role of Bradykinin in Microbial Infection: Enhancement of Septicemia by Microbial Proteases and Kinin.Kinin Antagonists as Human Therapeutics.Proteases in Immunoregulation and Cellular Differentiation.Cytokine Regulation of Endothelial Cell Extracellular Proteolysis.Different Functional Share of Individual Lysosomal Cathepsins in Normal and Pathological Conditions.Neuropeptide Processing in Pathophysiology.Resolution of limp-Free and Timp-Complexed 70kDa Progelatinase from Culture Medium of Rous Sarcoma Virus-Transformed Chicken.Endotoxin and Eicosanoids.