Methods and Applications of Sample Size Calculation and Recalculation in Clinical Trials

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Focusing on the principles and methods of sample size calculation in clinical trials, this book emphasizes the importance of determining the appropriate sample size for ethical, scientific, and economic reasons. It addresses the implications of both insufficient and excessive sample sizes, highlighting the necessity for advanced techniques in trial planning. Readers will gain insights into ensuring the success of clinical trials through meticulous sample size assessment and recalibration.