Knihu momentálně nemáme skladem
Více o knize
Neurofibromatosis type 1 (NF1) is an inherited tumor predisposition syndrome affecting 1 in 3,000 to 4,000 people globally, caused by mutations in the NF1 gene on chromosome 17. This gene produces neurofibromin, a crucial tumor suppressor protein that regulates Ras activity. The dysregulation of Ras leads to heightened signaling through the PI3K/AKT/mTOR pathway, which plays a vital role in cell survival and proliferation. Understanding NF1's genetic and molecular mechanisms is essential for developing targeted therapies.
Nákup knihy
The Molecular Biology of Neurofibromatosis Type 1, Meena Upadhyaya
- Jazyk
- Rok vydání
- 2014
- product-detail.submit-box.info.binding
- (měkká)
Jakmile ji vyčmucháme, pošleme vám e-mail.
Doručení
Platební metody
Navrhnout úpravu
- Titul
- The Molecular Biology of Neurofibromatosis Type 1
- Podtitul
- Neurofibromatosis Type 1
- Jazyk
- anglicky
- Autoři
- Meena Upadhyaya
- Vydavatel
- Biota Publishing
- Rok vydání
- 2014
- Vazba
- měkká
- Počet stran
- 80
- ISBN13
- 9781615046447
- Kategorie
- Příroda všeobecně
- Anotace
- Neurofibromatosis type 1 (NF1) is an inherited tumor predisposition syndrome affecting 1 in 3,000 to 4,000 people globally, caused by mutations in the NF1 gene on chromosome 17. This gene produces neurofibromin, a crucial tumor suppressor protein that regulates Ras activity. The dysregulation of Ras leads to heightened signaling through the PI3K/AKT/mTOR pathway, which plays a vital role in cell survival and proliferation. Understanding NF1's genetic and molecular mechanisms is essential for developing targeted therapies.