SARS-CoV-2 Spike Protein Convergent Evolution

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The book delves into the genetic traits and structural changes of SARS-CoV-2 variants circulating globally, focusing on their evolution across different regions during the pandemic. It examines the implications of these mutations on the effectiveness of existing neutralizing antibody-based vaccines and treatments, supported by recent clinical data. Additionally, the author proposes strategies to mitigate immune escape in future COVID-19 therapies, providing a comprehensive understanding of the ongoing challenges posed by these viral variants.