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Více o knize
Colm Duffy's thesis explores stable lipoxin analogues' chemistry and biology. He synthesized a pyridine-containing LXA4 analogue in enantiomerically pure form and found that both epimers suppress key cytokines in inflammatory diseases, with the (R)-epimer being the most effective. He also developed a thiophene-containing analogue with notable biological activity, inspiring further research.
Nákup knihy
Heteroaromatic Lipoxin A4 Analogues, Colm Duffy
- Jazyk
- Rok vydání
- 2014
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Doručení
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- Podtitul
- Synthesis and Biological Evaluation
- Jazyk
- anglicky
- Autoři
- Colm Duffy
- Vydavatel
- Springer, Berlin
- Rok vydání
- 2014
- Vazba
- měkká
- Počet stran
- 152
- ISBN13
- 9783642438929
- Série
- Springer Theses
- Štítky
- Naučná literatura
- Anotace
- Colm Duffy's thesis explores stable lipoxin analogues' chemistry and biology. He synthesized a pyridine-containing LXA4 analogue in enantiomerically pure form and found that both epimers suppress key cytokines in inflammatory diseases, with the (R)-epimer being the most effective. He also developed a thiophene-containing analogue with notable biological activity, inspiring further research.